As the most widely used viral vector for gene therapies, Adeno-Associated Viruses (AAVs) present unique advantages, including their ability to enter both dividing and non-dividing cells, the absence ...

Adeno-associated viruses (AAVs) have transformed the landscape of gene therapy product development. In the past, allocating precious samples for aggregate testing was completely impractical given the ...

SEC is a chromatographic technique that separates various analytes in a sample based on their hydrodynamic radius. It is commonly used for biologics to detect aggregates or degradants under native ...

Several quality attributes (QAs) must be monitored to ensure an effective and safe final product when developing adeno-associated virus (AAV) vectors as drug products. Thermal stability, aggregate ...