A class of drugs already on the market to lower blood pressure appears to reduce adults' risk of developing epilepsy, Stanford Medicine researchers and their colleagues have discovered. The finding ...

Role of the RAAS in the Pathophysiology of Heart Failure ACE inhibitors have no effect on angiotensin II formed by alternate pathways. In contrast, ARBs would be expected to inhibit the biologic ...

Hypertension control is critical to prevent stroke. With several clinical trials conducted over the last decade, it seems that the use of an angiotensin-modulating antihypertensive agent conveys ...

Diastolic dysfunction with ventricular stiffening and diffuse fibrosis underpins HFpEF, with hypertension, T2D, AF, CKD, CAD, and adiposity acting as key mechanistic and management modifiers.

Since the introduction of ARBs, the question that has pervaded each clinician’s mind is whether or not these drugs serve an advantage in conditions long addressed by ACE inhibitors. Matchar et al ...