Substance use disorders (SUDs) are highly heritable, but the extent of shared and distinct genetic architecture across ...

Substance use and substance use disorder differ by the frequency of use and the effect on a person’s life. Substance use disorder is a mental health condition. Substance use refers to using both legal ...

Researchers at the University of California San Diego have completed a massive genetic study that identifies key biological ...

Polysubstance use disorder is a mental health condition in which someone uses more than one substance at the same time or within a short period of time, despite a pattern of negative effects.

Clinical evidence has long suggested that the use of GLP-1 medications is linked to lower substance use. It’s also been speculated among patients taking the medications. Social drinkers, for example, ...

A new study has found differing patterns in the brain activity of boys and girls with a family history of substance use disorder, reflecting distinct ways in which they may be predisposed to addiction ...

Researchers explored the links between the adolescent dopamine system and cannabis use frequency, amount and addiction ...

Brain activity related to how young adults value reward appears to be linked to longer-term drinking patterns, according to a ...

What began as an unexpected observation and “side effect” of some medications converged with decades of addiction neuroscience: GLP-1 receptor agonist medications like Ozempic apparently reduce ...