Perhaps no cell type uses calcium in as many ways as does a cardiac myocyte. In addition to its well-known involvement in regulating cardiac contractility, recent studies have emphasized the ...

Glycine, a non-essential amino acid derived from serine, plays an increasingly recognized role in metabolic regulation.

A study has found an unexpected new link between inflammation in heart muscle following a heart attack and a previously known enzyme called calcium/calmodulin-dependent protein kinase II or CaM kinase ...

Cells attaching to an extracellular matrix through integrins flatten out (spread) on the matrix, eliciting cellular signals needed for survival. We show that the shape of the nucleus changes and the ...

Background: Wnt signaling affects fundamental development pathways by regulating cell proliferation and differentiation. Aberrant activation of Wnt/ß-catenin signaling promotes the development of ...

It is vital to the regulation of cell activities through its role as a second messenger. Calcium signaling is the process whereby low cytoplasmic concentrations are deliberately increased to activate ...

This is a preview. Log in through your library . Abstract Systemic acidosis has detrimental effects on the skeleton, and local acidosis coincides with bone destruction in inflammatory and metastatic ...