Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

A groundbreaking study has uncovered how specific genetic mutations influence cancer treatment outcomes -- insights that could help doctors tailor treatments more effectively. The largest study of its ...

The gene p53 acts as a tumor suppressor and often is called the ‘guardian of the genome.’ This gene is central to maintaining genomic stability, which prevents mutations from accumulating and leading ...

A new study from the University of Michigan Rogel Health Cancer Center, published in Science, sheds light on how two distinct classes of mutations in the FOXA1 gene—commonly altered in prostate cancer ...

The American Cancer Society estimates that over 80,000 individuals will be diagnosed with bladder cancer this year.

Researchers have pinpointed what could be the early genetic origins of breast cancer -- cancer-like mutations appearing in the cells of healthy women. In a new study, the international collaborators ...

Scientists have developed a blood test that can help predict which breast cancer treatment will work best. The team at the ...