Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Making proteins for research or therapies often starts with cell-line development. In many applications, genetic engineering is used to optimize a cell line for producing high levels of the intended ...

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...

A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...

Cell-surface proteins are critical therapeutic targets and are vital to cellular communication, signaling, and homeostasis.

Tissue processing advance can label proteins at the level of individual cells across whole, intact rodent brains and other large samples just as fast and uniformly as in dissociated single cells. A ...

A comprehensive mini-review published today after peer review in Brain Medicine by Dr. Tao Ma and colleagues at Wake Forest ...

Not only have researchers identified how a common cellular protein affects aging, but they’ve tweaked the genes that produce it in fruit flies, extending healthy lifespan by 25% to 30%. The discovery ...

Some parts of our bodies bounce back from injury in fairly short order. The outer protective layer of the eye—called the ...

Recent research has identified a specific biological mechanism that may explain why females experience more severe ...