New potential for Alzheimer disease biomarker testing found in dried blood collection derived from capillary blood.

Although peripheral samples are far easier to obtain from humans than more invasive central ones [e.g., cerebrospinal fluid (CSF) samples], their functional significance is unknown. This is because ...

Cerebrospinal fluid is the liquid around your brain and spinal cord. If a doctor thinks you have an illness that affects your nervous system, they might take a sample for testing. The fluid is made by ...

Sequencing circulating tumor cell-free DNA (cfDNA) in cerebrospinal fluid (CSF) improved diagnosis, decision-making, and clinical care in pediatric and adolescent and young adult (AYA) patients with ...

A technology that diagnoses various diseases, including Alzheimer’s and Parkinson’s, using just a few drops of blood from a ...

CSF-ctDNA was detected in 59% of cases and showed high concordance (84%) with tumor mutations. Lower variant allelic frequency in CSF-ctDNA was associated with significantly worse survival outcomes.

Between February 1995 and September 2005, 171 sibling donors (M/F: 98/73) with a median age of 42 years (range, 11–72) underwent PBPC collection at our institution. Donor characteristics are shown in ...

The cannulation of the cisterna magna in the rat is a valuable model for in-vivo sampling of cerebrospinal fluid for studying delivery of new drugs into the central nervous system or disease models.