Faulty lipid regulation in CLL patients impairs T-cell function, affecting treatment outcomes and resistance to current therapies. Differences in lipid metabolism between CLL patients and healthy ...
For the roughly 200 million people worldwide who take a statin every day, the routine is deceptively simple: swallow a pill, ...
B cell activation and antibody class switching requires coordinated metabolic rewiring, with essential roles for amino acid transport, cholesterol metabolism, and prenylation in driving proliferation ...
Researchers suggest targeting mTOR activity in aggressive cancers by blocking cholesterol sensing may represent a promising ...
Cardiovascular disease is the leading cause of death in the United States and worldwide, driven largely by atherosclerosis, the build-up of cholesterol-rich plaques both in and on the arteries. Early ...
In a recent review published in the journal Experimental & Molecular Medicine, researchers reviewed available literature on the role and mechanisms (molecular and pathological) by which cholesterol ...