An unexpected lab observation has led a team of scientists to discover how diet can influence survival in animal models of ...

Chromatin is a structure in the cell nucleus that helps pack DNA tightly by wrapping it around proteins called histones. These DNA-protein units, called nucleosomes, control how genes are turned on or ...

A study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior. Chromatin, the compact form of DNA, not only packages genetic material but also ...

Here we investigate the role of epigenetics in the formation, transcription regulation, maintenance and termination of several non-canonical chromatin structures. Using two examples, we demonstrate ...

In response to an infection, a wide range of cells in innate and adaptive immune systems are activated, and then they collaborate to control and eliminate invading pathogens 1,2. In immune response, ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

Genome-wide maps of chromatin structure in a cell-based model of breast cancer reveal chromatin reorganization accompanied by changes in transcription and epigenetic marks.

This study is led by Dr. Yue Zhou (State Key Laboratory of Gene Function and Modulation Research, School of Advanced Agricultural Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, ...

A recent study has shed light on the transcriptional regulatory mechanisms of Penicillium expansum, the fungal culprit behind blue mold disease in fruits. By mapping chromatin accessibility at ...

In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be helpful for learners to begin with the linear presentation of how ...

We were delighted to have had the chance to sit down with Cigall Kadoch, Professor at the Dana-Farber Cancer Institute ...