What’s the difference between High Performance Liquid Chromatography (HPLC) and Ion Chromatography (IC)? What are the capabilities and limitations of each technique? Knowing these differences can ...

High-performance liquid chromatography or high-pressure liquid chromatography (HPLC) is a chromatographic method that is used to separate a mixture of compounds in analytical chemistry and ...

When conducting reproducible and interference-free analysis by liquid chromatography, the purity of the solvents used, particularly the purity of water, is crucial for the sensitivity of this method, ...

As analytical technology continues to advance, both regulatory agencies and pharmaceutical companies are keen to avail themselves of these enhancements. In the case of chromatography, evolution from ...

For some chromatographers, their first inkling that high-performance liquid chromatography was going to be a big deal came in 1969. That year, they traveled to Las Vegas to attend the fifth in a ...

Investigation of peak purity failure during HPLC method validation led to discovery of a co-eluting impurity under the main peak. Spectral analysis, including three-dimensional modelling, was used to ...

High-performance liquid chromatography (HPLC) gives chemists access to a world of knowledge about molecules both large and small. When combined with high-resolution detection methods such as mass ...

The use of acidic MPAs (pH 2–4) is the default in pharmaceutical testing because they suppress silanol ionization (from Si-OH to Si-O -) and improve peak shape for basic drugs. However, highly ...

Waters Corporation (NYSE: WAT) announced that more than 40 products within its liquid chromatography (LC) chemistry portfolio have obtained Accountability, Consistency, and Transparency (ACT) ...