Please provide your email address to receive an email when new articles are posted on . Aspirin did not improve DFS for individuals with colorectal cancer liver metastases compared with placebo. OS ...
PDS01ADC is a tumor-targeted IL-12 immunocytokine designed to activate the immune system directly within the tumor ...
The efficacy of watch and wait strategy or surgery after neoadjuvant immunotherapy for locally advanced colorectal cancer with dMMR/MSI-H guided by ctDNA dynamic monitoring (WINDOW): A single-center, ...
Acoustic cluster therapy combined with chemotherapy showed a 29% tumor diameter reduction, compared to 7% with chemotherapy alone in colorectal liver metastases. The therapy uses PS101, activated by ...
Resection of liver metastases is considered the only treatment with curative potential for patients with metastatic colorectal cancer to the liver (CRLM). However, only a minority of patients with ...
A new international study led by Mayo Clinic researchers has identified a genetic factor that may explain why some patients with colorectal cancer that has spread to the liver experience more severe ...
Objective Response Rate (ORR) with PDS01ADC; Parallel trial without PDS01ADC had 35% ORR 2-year survival rate of >80%; Parallel trial without PDS01ADC resulted in 2-year survival rate of ~35% Trials ...
(A) It was shown low expression of OXCT1 in liver metastasis in datasets GSE41258, GSE68468, GSE35834. Student's t - test was used to calculate p value. (B) The expression of OXCT1 was low in paired ...
Lipid deposition promotes CRC progression and metastasis via YTHDF3-mediated m 6 A modification of PPARα and inhibition of β-Hydroxybutyrylation. Lipid Metabolism & Clinical Impact: • Significant ...
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