Normal urinary bladder function requires contraction and relaxation of the detrusor smooth muscle (DSM). The DSM undergoes compensatory hypertrophy in response to partial bladder outlet obstruction ...

A new molecular pathway has been identified that is critical for maintaining the smooth muscle tone that allows the passage of materials through the digestive system. Researchers at UMass Medical ...

A research group led by Dr. Keisuke Obara, Dr. Kento Yoshioka, and Professor Yoshio Tanaka from the Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, has ...

Researchers at UT Southwestern Medical Center at Dallas are the first to use genetically engineered mice containing a fluorescent molecule to examine in real time the chemical reactions that result in ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...