(HealthDay News) — Concerns about safety of metformin in renal impairment may be unnecessarily preventing its use in type 2 diabetes mellitus (T2DM), according to a research letter published online ...

To check for renal insufficiency and ward off complications, such as lactic acidosis, I calculate the creatinine clearance of my diabetic patients taking metformin (Glucophage). At what creatinine ...

Study reveals a 35% increase in all-cause mortality risk compared with non-use. Metformin use by patients with stage 5 chronic kidney disease (CKD) may be an independent risk factor for early death, a ...

September 21, 2012 — Metformin was associated with a lower risk for cardiovascular disease, all-cause mortality, and serious infection/acidosis compared with insulin in a large database analysis of ...

A recent study, [1] conducted by three pharmacists and a nurse, explores why only 65% of patients with newly diagnosed type 2 diabetes (T2DM) and only 25% of people with ongoing T2DM are prescribed ...

Glyburide, metformin HCl; 2.5mg/500mg, 5mg/500mg; tabs. Take with meals. Individualize. Not controlled on diet/exercise (use individual components): initially glyburide 1.25mg and metformin 250mg once ...

Saxagliptin, metformin HCl (ext-rel); 5mg/500mg, 5mg/1000mg, 2.5mg/1000mg; tabs. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones, thereby increasing ...

Although metformin has been the go-to medication to manage type 2 diabetes for more than 60 years, researchers still do not have a complete picture of how it works. Scientists at Baylor College of ...