The process of cell division is central to life. The last stage, when two daughter cells split from each other, has fascinated scientists since the dawn of cell biology in the Victorian era. For just ...

Scientists have elucidated the molecular mechanism by which LEM-3 cuts DNA bridges during cytokinesis. If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally ...

Study finds that large embryo cells divide step by step using a mechanical ratchet system, challenging the textbook idea of a ...

Scientists have uncovered a surprising new way that giant embryonic cells divide—without relying on the classic “purse-string” ring long thought essential for splitting a cell in two. Studying ...

Accurate chromosome segregation and cell division are central to maintaining genomic integrity and ensuring proper development and tissue homeostasis. These processes rely on a complex network of ...

Functional analysis of the LEM-3 protein and the roles of its domains using the C. elegans model. (A) Evidence shows that LEM-3 accumulates at DNA bridges remaining between daughter cells during the ...