People living with Alzheimer’s disease are likely going to require a great deal of care. How much they rely on others to perform daily tasks for them will depend on the severity of symptoms, on when ...

In a new study, researchers from the Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease. This ...

Scientists at Scripps Research published findings that demonstrate how a mitochondrial protein structure is necessary to activate the cell’s integrated stress response (ISR), which is a critical ...

Solving the structure of an amyloid protein gives new insight into limb-girdle muscular dystrophy type 3 (LGMD D3) and functional protein aggregation. LGMD D3 is a rare disease characterized by slow ...

Visualization of the protein clumps associated with Huntington’s disease, determined by combining simulations and multiple complementary types of experiments. The figure shows the overall structure at ...

Devastating neurodegenerative diseases like Huntington's, Alzheimer's, and Parkinson's are all associated with protein deposits in the brain, known as amyloid. Despite extensive research investment ...