Osaka, Japan – The immune system is tightly regulated to ensure that it only responds to actual health threats, instead of attacking our own bodies, which happens in cases of autoimmunity. Now, ...

The immune system faces a delicate balancing act: it must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues. More than two decades ...

The immune system faces a delicate balancing act: It must be aggressive enough to fight infections and cancer, yet restrained enough to avoid attacking the body's own tissues. More than two decades ...

Sakaguchi's 1995 discovery of regulatory T cells revealed a complex immune tolerance system beyond central tolerance. Brunkow and Ramsdell identified the Foxp3 gene mutation in 2001, linking it to ...

Using a CRISPR screen, scientists at the Salk Institute have discovered a genetic “dial” to turn immune function up and down. The scientists suggest that the dial, which affects the development and ...

A team of scientists from the Perelman School of Medicine at the University of Pennsylvania and Aum Biotech LLC have described the development of a novel cancer immunotherapy designed to target ...

Rosa Bacchetta is an associate professor of pediatrics at Stanford University. Her goal as a physician-scientist is to use modern technologies in the laboratory to find cures for untreatable pediatric ...

A team of scientists—including Jenny Umhoefer, seen here—uncover potential clues for future autoimmunity and cancer treatments by learning to fine-tune a gene that is centrally involved in regulating ...