To discover novel hepatitis C virus (HCV) inhibitors and elucidate the mechanism of action of the active compounds. For the purpose of developing and studying novel anti-HCV drugs, we screened 1200 ...

At doses corresponding to estimated human doses, 24 hour trough plasma concentrations of ANA598 exceeded the EC95 for HCV genotype 1a and 1b replicon inhibition. The EC95 is the concentration required ...

There's a camp that says innovation in drug development comes solely from academia and government labs. Another says the pharmaceutical industry invents drugs, without academic involvement. Both camps ...

Researchers at the University of Pennsylvania have demonstrated that morphine withdrawal complicates hepatitis C by suppressing IFN-alpha-mediated immunity and enhancing virus replication. The paper ...

A rapid, reliable, point-of-care HCV assay has been developed. In 2016, the WHO therefore published a plan to eliminate this major threat for public health by 2030. An assay that detects HCV RNA as ...

Beckman Coulter Diagnostics has obtained CE Marking for its DxN VERIS HCV Assay, a real-time PCR assay for the rapid and reliable quantitative determination of Hepatitis C Virus (HCV) RNA in human ...

A team of NIH-supported researchers today report that alcohol increases replication of the hepatitis C virus (HCV) in human cells and, by so doing, may contribute to the rapid course of HCV infection.

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Philadelphia, PA—Researchers at the University of Pennsylvania have demonstrated that morphine withdrawal complicates hepatitis C by suppressing IFN-alpha-mediated immunity and enhancing virus ...

Beckman Coulter Diagnostics has obtained CE Marking for its DxN VERIS HCV Assay, a real-time PCR assay for the rapid and reliable quantitative determination of Hepatitis C Virus (HCV) RNA in human ...