UCLA Health researchers have created a comprehensive map showing how eight different genetic mutations associated with autism ...

Schizophrenia is a highly heterogeneous psychiatric disorder affecting ~1% of the global population, typically emerging in ...

A new study published in Nature in the paper, “Developmental convergence and divergence in human stem cell models of autism,” provides new insights by demonstrating that while different mutations ...

Most cancers are not driven by a single gene mutation, but rather an accumulation of mutations that develop over the evolution of tumor growth. While mouse models are useful for identifying cancer ...

Please provide your email address to receive an email when new articles are posted on . NASHVILLE, Tenn. — An analysis of germline susceptibility to renal cell carcinoma revealed considerable ...

Despite the development of cutting-edge genetic testing techniques and considerable progress in our understanding of the genetic basis of idiopathic pulmonary fibrosis (IPF), missing heritability and ...

Using cortical organoids from individuals with autism, researchers tracked gene activity over development. Early ...

Forty-five years ago adult AL was incurable. Since then we have discovered the striking heterogeneity of AL and its importance in selecting therapy, resulting in cure of increasing numbers of patients ...

Charcot-Marie-Tooth (CMT) disease is a group of clinically and genetically heterogeneous sensorimotor peripheral neuropathies. It is the most frequent inherited neuromuscular disorder affecting 9.7-82 ...

The power of CRISPR became definitively clear when the first CRISPR-based gene therapy, Casgevy (exa-cel), won regulatory approvals for the treatment of sickle cell disease. But CRISPR’s applications ...