BACKGROUND: Aortic valve calcification increases leaflet stiffness and contributes to the development of calcific aortic valve disease. The molecular and cellular mechanisms underlying calcification ...

BACKGROUND: There is limited evidence of the relationship between aortic and iliac calcification and aortic events (aortic dissection or aneurysm rupture) and major adverse limb events (MALEs; ...

A team of scientists has identified an unexpected embryonic "starting point" for several brown-fat depots: a small cell niche around the dorsal aorta. Using a combination of time-controlled genetic ...

They were able to show that endothelial cells that line the tissue play a major role, as is the case with other vascular diseases. In addition, they were able to see that what happens varies greatly ...

Studying the cells of people and genetically engineered mice, scientists say they have uncovered a potential reason why patients with Loeys-Dietz syndrome, an inherited connective tissue disorder, are ...