Immunoglobulins (Ig) are important effector molecules of adaptive humoral immune responses. Production of antibodies to innocuous antigens is a reflection of a normal immune response. In allergic ...

Cetuximab, a chimeric mouse–human IgG1 monoclonal antibody against the epidermal growth factor receptor, is approved for use in colorectal cancer and squamous-cell carcinoma of the head and neck. A ...

Please provide your email address to receive an email when new articles are posted on . Cephalosporins appeared to be the leading causes of beta-lactam hypersensitivity, especially in reactions that ...

Anaphylaxis is a life-threatening immediate hypersensitivity reaction triggered by antigen capture by immunoglobulin E (IgE) bound to the high-affinity IgE receptor (FcɛRI) on mast cells. However, the ...

Determining true HER2 status in breast cancers with polysomy using alternative chromosome 17 reference genes: Implications for trastuzumab therapy. Background: Cetuximab is increasingly used in ...

Meat is an important part of the Western diet but anaphylaxis is rare. This is explained by the fact that most proteins in human and animal meat are homologous, preventing the emergence of IgE ...