Indole, and structures derived from it, are a component of many natural substances, such as the amino acid tryptophan. A new catalytic reaction produces cyclopenta[b]indoles -- frameworks made of ...

A research group at Nagoya University in Japan has successfully developed an ultrafast and simple synthetic method for producing indole derivatives. Their findings are expected to make drug production ...

Scientists have cracked one of chemistry’s toughest challenges with indoles, using copper to unlock a spot once thought too stubborn to change. The discovery could pave the way for easier, cheaper ...

Indole, a molecule made up of a six-membered benzene ring fused to a five-membered ring containing nitrogen, forms the core structure of many biologically active compounds. Derivatives of indole, ...

A cost-effective copper-catalyzed reaction enables selective modification at the C5 position of the indole ring, a backbone for pharmaceutical compounds Indole, a molecule made up of a six-membered ...

Flowering plants need indole: Indole is important for plant defense and for attracting pollinators. Indole biosynthesis occurs via a pseudoenzyme: Although TSB-like is essential for indole formation, ...

Scientists have achieved a new feat in molecular editing by swapping carbon for nitrogen, enabling the direct conversion of indoles into benzimidazoles. This simple switch in a one-pot method offers a ...

You’ve undoubtedly smelled indole. Perfumers add it to flowery fragrances, but it’s also added to chocolates, coffees, and fruity-flavored sweets. That doesn’t sound bad—until you learn that ...