In a recent study posted to the bioRxiv* preprint server, researchers assessed the roles of the interferon (IFN) regulatory factors (IRFs): IRF1, IRF3, and IRF7 in infections by human coronaviruses ...

Interferons are proteins that are part of your natural defenses. They tell your immune system that germs or cancer cells are in your body. And they trigger killer immune cells to fight those invaders.

Impaired termination of immune responses is detrimental and often results in chronic inflammation and disease. Most activated T cells and B cells die after antigen clearance, and only a small fraction ...

Interferons are a basic way that our bodies fight everything from the sniffles to certain cancers. Released by cells when threatened, these proteins tell nearby cells to, in a sense, “interfere” with ...

One of the body's first protective reactions to infection is inflammation, typically stimulated by the factor IL-1beta. Unfortunately, inflammation frequently occurs when it is not desired and so must ...

Researchers have gained new insight into the early stages of our immune response, providing novel pathways to develop treatments for diseases from multiple sclerosis to cancer. Monash University ...

New Rochelle -- Inhaled interferon-gamma may be an effective treatment for idiopathic pulmonary fibrosis (IPF), a chronic and progressive form of lung disease caused by excessive formation of fibrotic ...

Antiviral therapy without interferon improved liver function in patients with hepatitis C virus infection-related advanced cirrhosis, according to data from an observational cohort study. Researchers ...

Inhaled interferon-gamma may be an effective treatment for idiopathic pulmonary fibrosis (IPF), a chronic and progressive form of lung disease caused by excessive formation of fibrotic, or scar tissue ...