In a recent study published in Science Immunology, researchers investigated whether individuals with breakthrough infections of severe coronavirus disease 2019 (COVID-19) pneumonia demonstrated normal ...

Interferons are a basic way that our bodies fight everything from the sniffles to certain cancers. Released by cells when threatened, these proteins tell nearby cells to, in a sense, “interfere” with ...

Impaired termination of immune responses is detrimental and often results in chronic inflammation and disease. Most activated T cells and B cells die after antigen clearance, and only a small fraction ...

In a recent study posted to the bioRxiv* preprint server, researchers assessed the roles of the interferon (IFN) regulatory factors (IRFs): IRF1, IRF3, and IRF7 in infections by human coronaviruses ...

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have ...

Research presented by Professor Cecilia Johansson of Imperial College London has linked early type I interferon signalling in ...

In Part I of this article, which appeared in the January 2022 issue of GEN, William A. Haseltine, PhD, discussed findings that can help us understand why some people resist COVID-19 more effectively ...

More than seven million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's ...

Despite potential benefits, the therapy remains in limited use for myeloproliferative neoplasms (MPNs). Pegylated interferons are a meaningful therapeutic option for the treatment of ...

More than 7 million Americans have Alzheimer's disease, and two-thirds of them are women, according to the Alzheimer's ...