Long before a liver tumor appears, a high-fat diet can push liver cells into a risky survival mode. That is the central ...

From fast-food to ultra-processed snacks, a high-fat diet eaten over the long term may trigger biological changes in the ...

Salk Institute scientists discovered that bile acids in the liver can weaken immune cell function, making immunotherapy less effective against liver cancer. They pinpointed specific bile acids that ...

Glycolysis is a central metabolic pathway by which cells obtain energy from sugar. Cancer cells in particular have long been ...

Scientists have uncovered how fatty liver disease, fueled by high-fat, high-sugar diets, can stealthily evolve into liver cancer. When liver cells experience DNA damage from such diets, they often ...

Liver cancer cells thrive on fat, posing a serious risk of cancer diagnosis for millions of people living with fatty liver disease. But researchers at McMaster University in collaboration with ...

Scientists identify measurable cellular changes that flag higher cancer risk more than a decade before tumors appear. In A ...

MASLD and Liver Cancer: What’s the Link? Metabolic dysfunction-associated steatotic liver disease (MASLD) is a condition where too much fat builds up in your liver. Unlike fatty liver caused by heavy ...

A novel 3D cell culture method has been developed that encourages liver progenitor cells to self-organize and form blood vessel networks for the first time. The development of accurate liver organoids ...