High-risk constitutional MLH1 methylation underlies a significant proportion of early-onset endometrial cancers and colorectal cancers with tumor MLH1 methylation. At the American Society of Clinical ...
Mismatch repair (MMR) immunohistochemistry (IHC) is frequently used to inform prognosis, select (immuno-)therapy, and identify patients for heritable cancer syndrome testing. However, false-negative ...
Highly Sensitive Circulating Tumor DNA Assay Aids Clinical Management of Radiographically Occult Isolated Peritoneal Metastases in Patients With GI Cancer These cases highlight the challenges in ...