Metathesis reactions are chemical reactions in which two hydrocarbons (alkanes, alkenes or alkynes) are converted to two new hydrocarbons by the exchange of carbon–carbon single, double or triple ...

Scientists who’ve lost sleep over the metathesis reaction’s preference for forming E olefins can finally catch some Zs—Z olefins, that is. Using specially designed molybdenum catalysts, chemists have ...

Bicyclic peptides are promising scaffolds for the development of inhibitors of biological targets that proved intractable by typical small molecules. So far, access to bioactive bicyclic peptide ...

In 2005 and 2006, Boehringer Ingelheim researchers published what they claimed was the first reported scale-up of a ring-closing metathesis (RCM) reaction to make a macrocyclic hepatitis C protease ...