The most common genetic cause of hereditary deafness in humans are mutations in the GJB2 gene, especially the 35delG and 235delC mutations. At the recent ARO meeting, researchers from Ear Nose and ...

Researchers restored hearing in preclinical mouse models with a specific form of inherited deafness called DFNA50 caused by mutations in microRNA, by using a novel in vivo CRISPR genome editing ...

For those born with certain types of congenital deafness, the cochlear implant has been a positive and enabling technology.

Demonstrated significant hearing restoration in blast-induced sensorineural hearing loss models Promoted significant functional recovery and axonal regeneration in peripheral nerve injury models ...

Five children who were born completely deaf have had some reversal of hearing loss after receiving a “groundbreaking” gene therapy. The clinical trial, which was co-led by Mass Eye and Ear in Boston ...

The study also looked at safety of the AAV-mediated genome editing approach and found it had a good safety profile that includes little off-target effect and no detectable long-term integration of the ...