With the introduction of adaptive deep brain stimulation (aDBS) for Parkinson's disease, new questions emerge regarding who, why, and how to treat. This paper outlines the pathophysiological rationale ...

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Experiments mapping individual neurons in the sensorimotor cortex of mice show that sharp transitions in functional properties can define cortical regions.

Deep brain stimulation (DBS) improves motor symptoms of Parkinson's disease by modulating a specific brain network that is mainly active in the fast beta frequency range (20 to 35 Hz). This conclusion ...

Chronic refractory pain syndromes often have a complex natural history and unclear aetiology. Pain may be nociceptive, neuropathic or deafferentation or in some cases, of uncertain origin. Treatment ...

Researchers have uncovered a fast-acting brain network that may determine how effectively deep brain stimulation improves Parkinson’s symptoms. Parkinson’s disease can make everyday movements slow, ...

Researchers have uncovered a major clue about what causes Parkinson’s disease, a progressive brain disorder that affects movement, sleep, and thinking. An international team led by scientists in China ...

An international team of scientists led by the University of Surrey has discovered that a form of safe, painless, and non-invasive brain stimulation could help people who are at risk of falling behind ...