Testicles of most mammals are cooled in the scrota, and elevated testicular temperatures lead to spermatogenesis failure and male infertility. A research team led by Shosei Yoshida at the National ...

Among their many functions, macrophages in mouse testes guard sperm against attacks by other immune cells. Will this year’s Nobel Prizes go to GLP-1 research, optogenetics, or something else?

For the first time, scientists have grown three-dimensional, miniature versions of testicles in the lab, using mouse cells. The lab-grown testicles survived in a dish for up to nine weeks and closely ...

For species that rely on sexual reproduction, including mice and men, offspring can only happen if sperm from the male fertilize eggs from the female. Even artificial fertilization techniques depend ...

A breakthrough study published in PLoS Biology demonstrates that rat testis tissue frozen for over 20 years can be successfully transplanted into infertile mice to regenerate and produce sperms.

A testis produced from human cells, for example, could help children being treated for cancer, which may impair their ability to produce functional sperm. As children are too young to produce their ...