A biomarker test identified tau pathology in Alzheimer's disease before fibrillary tangles developed. Neurofibrillary tangle formation can be prevented by targeting intermediate soluble tau assemblies ...

A spectrum of neurodegenerative diseases, including frontotemporal dementia (FTD), progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD) are due to the accumulation of abnormal, ...

We're talking octogenarians (or older) with faculties more like their 50s. Here's what Northwestern cognition researchers found they're doing right.

Why do memories falter with age? In a preprint posted on bioRxiv on May 22, scientists led by Omer Sharon and sleep researcher Matthew Walker at the University of California, Berkeley, suggested that ...

Today we begin a several-part series on Alzheimer’s disease, the most common cause of memory loss and dementia. Alzheimer’s is a brain disease characterized by amyloid plaques and neurofibrillary ...

Clinicians may soon have a blood test for neurofibrillary tangles. At AAIC 2024, held July 27-31 in Philadelphia, Randall Bateman, Washington University, St. Louis, reported that a fragment of tau ...

Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the University of Pittsburgh School of Medicine can detect small amounts of the ...

In people with no thinking and memory problems, a simple test may predict the risk of developing cognitive impairment years later, according to a study published in the April 19, 2023, online issue of ...

Down syndrome is caused by an extra copy of chromosome 21. Because of genes present on this chromosome that are known to contribute to Alzheimer's disease, patients with Down syndrome often develop ...