DNA, often called the blueprint of life, is built from four chemical building blocks known as deoxy-nucleoside triphosphates (dNTPs)—dATP, dTTP, dGTP, and dCTP. Cells constantly need these molecules ...

A team of researchers from the Department of Biological Sciences at UNIST has achieved a significant breakthrough in understanding how brain proteins can help alleviate complications arising from DNA ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral ...

Memorial Sloan Kettering Cancer Center investigators and collaborators have tested rezatapopt, an oral p53 reactivator designed for tumors with TP53 Y220C, and observed antitumor activity across ...

HBV is a partially double-stranded DNA virus. The life cycle and therapeutic targets are shown in Figure 1 and Figure 2. The spherical 42-nm virion comprises an envelope that is outside a 30-nm ...

The replication of potentially harmful adenoviruses can be significantly reduced in human cells in cell culture by using the so-called CRISPR-Cas9 system ("gene scissors"). This method, which is used ...

In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would later reshape biology and our understanding of life itself. A ...