Primary biliary cholangitis (PBC), formerly known as primary biliary cirrhosis, and primary sclerosing cholangitis (PSC) both involve the breakdown of your bile ducts. Both conditions are also thought ...

Primary biliary cirrhosis, primary sclerosing cholangitis and autoimmune hepatitis are the three major immune-mediated liver diseases. The etiologies of primary biliary cirrhosis, primary sclerosing ...

Please provide your email address to receive an email when new articles are posted on . The liver’s production of bile acids is interwoven with the gut’s diverse microbial community. Despite treatment ...

In a Healio exclusive, Gideon Hirschfield, PhD, MB BChir, the Lily and Terry Horner Chair in Autoimmune Liver Disease Research at University of Toronto, discusses key considerations when diagnosing ...

Cholestatic liver diseases (CLDs) are a group of disorders characterized by the impairment of bile formation, secretion, or excretion. This impairment leads to bile acid accumulation in the liver, ...

Primary biliary cholangitis (PBC) is an autoimmune disorder that leads to the destruction of bile ducts within the liver. As more bile ducts become lost and damaged, bile acids build up within the ...

FOSTER CITY, Calif.--(BUSINESS WIRE)--Mirum Pharmaceuticals, Inc. (Nasdaq: MIRM) today announced interim results from two Phase 2b studies evaluating volixibat, an oral ileal bile acid transporter ...

Sclerosing cholangitis and primary biliary cirrhosis, which is now called primary biliary cholangitis (PBC), are chronic cholestatic liver diseases, but they differ in their causes, affected bile ...

Apoptosis seems to play an important role in the pathogenesis of immune-mediated liver diseases. Death receptor ligands and marker molecules that are involved in apoptosis can be detected at increased ...