Indoor tanning is associated with markedly higher mutation burdens and cancer-driving genetic changes in melanocytes taken ...

Relationship Among DNA Damage Response Gene Alterations, Molecular Subtypes, and Survival Outcomes in Patients With Metastatic Bladder Cancer Treated on CALGB 90601 Sequencing data from 56,965 ...

Scientists depicted the four-dimensional genome model to reveal how DNA folding regulates genes. The discovery helps ...

Lenvatinib and pembrolizumab in patients with metastatic papillary renal cell carcinoma: A phase 2 pilot study. Differences in the expression heterogeneity of ADC-related markers between primary ...

Tanning beds not only increase melanoma risk but also inflict a molecular toll, causing a spike in DNA mutations within skin ...

Using menopausal hormone therapy (MHT) was not associated with an increased risk of breast cancer in women with inherited ...

Due to the extremely rare overlap of mitochondrial DNA depletion syndrome type 3 and pediatric hepatocellular carcinoma, the case presents daunting therapeutic challenges.

A study of men with a family history of prostate cancer has discovered an inherited form of prostate cancer. The inherited mutated gene WNT9B, which functions normally in embryonic prostate ...

Repeat expansion disorders, which are responsible for more than 40 neurological diseases, may be more common than clinical data would suggest. Epidemiological studies had estimated that REDs affect ...

Natural pathogenic bacteria populations can harbour mutator alleles (with high mutation rates) that may offer a selection advantage. In the March 30 Science, Giraud et al. describe a model to ...