Bacterial cells often possess molecules of closed, circular DNA, otherwise known as ‘plasmids’. They can also be present at much lower frequencies in certain eukaryotic cell types, such as yeast. They ...
Gene therapies rely on plasmid DNA (pDNA). Consequently, continued growth in gene therapies is inseparable from continued growth in pDNA manufacturing. That growth seems assured. According to Grand ...
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Subverting plasmids to combat antibiotic resistance
Researchers in the Blavatnik Institute at Harvard Medical School have opened a new window into understanding the development of antibiotic resistance in bacteria. Subscribe to our newsletter for the ...
Gene editing is revolutionizing the understanding of health and disease, providing researchers with vast opportunities to advance the development of novel treatment approaches. Traditionally, ...
Researchers at the University of Oxford report that plasmids are one of the key culprits in spreading the major global health threat of antibiotic resistance. Using an Escherichia coli experimental ...
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Plasmid-borne resistance drives global expansion of dangerous Klebsiella strains
A recent study published in Engineering has shed light on the transmission and epidemiological trends of tmexCD1-toprJ1 ...
Advancements in technology and the increasing demand for improved, effective and innovative products to prevent, treat, and in some cases, cure diseases have focused the attention of drug developers ...
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