During an oral Spotlight Presentation, Codexis unveiled the successful end-to-end enzymatic synthesis of an entire approved siRNA therapeutic asset, inclisiran. Codexis enzymatically synthesized the ...

The beginning of life on Earth and its evolution over billions of years continue to intrigue researchers worldwide. The central dogma or the directional flow of genetic information from a deoxyribose ...

A novel chemo-enzymatic approach to making synthetic 100-unit oligonucleotide single guide RNA (sgRNA) increases both purity and yield, according to its developers at F. Hoffmann-La Roche and ...

RNA is fundamental to all life, governing gene expression, regulating biological processes, and influencing growth, development, and cellular metabolism. However, elucidating the precise mechanisms of ...