When the molecular machinery in our cells gets to work transcribing the genetic information encoded in DNA into messenger RNA (mRNA), it pauses shortly after starting. Known as promoter-proximal ...

Living cells are fundamentally nonequilibrium systems, meaning they constantly spend energy through seemingly one-way, irreversible processes, such as transcribing DNA into RNA, to keep life going.

Every living cell must interpret its genetic code - a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological ...

This month, Prof. Franklin Pugh, molecular biology and genetics, and researchers Chitvan Mittal grad, Olivia Lang grad, and William K.M. Lai grad, found that inducible systems work in conjunction with ...

Linear DNA templates let researchers bypass the additional cloning, purification, linearization, or amplification steps often ...

With a new study in the journal Cell, researchers at Stanford University and Stockholm University have contributed to increased knowledge about gene regulation in human cells. How genes are turned on ...