Transfection protocols and the reagents used to deliver nucleic acids into cells can affect cell physiology, leading to misinterpretation of results. Using microarray analysis and cell viability ...

In this interview, News Med talks to Hinnah Campwala about the pivotal role of transfection in modern research and drug discovery. Transfection is a tool that sees widespread use across a diverse ...

The ability to alter the genetic composition of living cells has revolutionized biology. Scientific advances, from treating genetic disorders through gene therapy to reprograming skin cells into ...

Transfection, a key genetic technology in the toolbox of many researchers, spans numerous applications—production of recombinant proteins and recombinant cell lines, drug discovery, delivery of ...

Hinnah Campwala (left) is a Principal Scientist in the Cell Biology Development Group at Sartorius BioAnalytical Instruments (Michigan, USA). With a background in drug discovery and immune cell ...

A Few Key Considerations Are Essential to Obtain the Best Return from Cell-Based Experiments Because optimal DNA delivery into mammalian cells depends on multiple factors, we recommend optimizing ...

Transfection is a crucial non-viral technique for introducing DNA or RNA into cells, yet achieving high efficiency and consistency can be challenging, particularly with difficult cell types.

Transfection remains a fundamental tool for investigating gene and protein function across diverse systems. Yet variability in constructs, cell types, and delivery methods often complicates ...

Gene therapy involves the transfer of genetically modified materials into a patient's cells to correct abnormal genes associated with diseases (Sun, 2017). Recent advancements in gene therapy have ...

Transfection is an essential cell biology technique by which one can introduce nucleic acids (DNA & RNA) into eukaryotic cells. It is particularly useful when one wants to express genetically ...

Polyethylenimine (PEI)-assisted transfection is a mainstay in upstream processing (USP) for viral vector manufacturing. But recent developments are shifting it from a ...