Autoimmune polyendocrine syndrome type 1 (APS-1) is a life-threatening, autosomal recessive syndrome caused by autoimmune regulator (AIRE) deficiency. In APS-1, self-reactive T cells escape thymic ...
Pain in rheumatoid arthritis often persists independently of joint inflammation. In this issue, Su et al. demonstrate that sustained non-canonical type 1 interferon signaling within peripheral sensory ...
A new study shows that about two percent of the population develop autoantibodies against type 1 interferons, mostly later in life. This makes individuals more susceptible to viral diseases like COVID ...
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