Reports on stem cell therapies for post-heart attack tissue repair have described at best modest success. Most clinical trials have used bone marrow-derived cells, which are thought to promote the ...
Knockout of multifunction gene cysteine- and glycine-rich protein 3 (CSRP3) in cardiomyocytes (CMs) of mice leads to heart dilation, severely affecting its functions. In humans, CSRP3 mutations are ...
Cardiotoxicity underlies a third of failures in regulatory clearance, making it among the most significant hurdles in developing new drugs. 1 axoCells human iPSC-derived ventricular cardiomyocytes ...
Researchers from the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) say that it is now possible for the first time to monitor the functional development and maturation of ...