Peroxynitrite ... Reactions of peroxynitrite leading to either apoptotic or necrotic cell death Peroxynitrite (sometimes called peroxonitrite) is an ion with the formula ONOO −. It is a structural isomer of …

Jun 1, 2024 · Peroxynitrite is a highly reactive oxidant formed from the reaction of superoxide radical with nitric oxide. The biological effects of peroxynitrite are due to oxidation and nitration reactions. In …

Although peroxynitrite is a strong oxidant, it reacts at a relatively slow rate with most biological molecules. With its reaction with carbon dioxide and other major reactions in cells taken into account, …

Peroxynitrite — the product of the diffusion-controlled reaction of nitric oxide with superoxide radical — is a short-lived oxidant species that is a potent inducer of cell death.

Jul 26, 2025 · Peroxynitrite is a highly reactive and damaging molecule that forms within the body. Its potent chemical nature allows it to interact with and modify numerous cellular components, altering …

Peroxynitrite (ONOO-), a product of the reaction of nitric oxide with superoxide, is a potent and versatile oxidant that can attack a wide range of biological molecules.

Reactive nitrogen species (RNS) are produced in biological systems starting with the reaction of NO with O 2 •− to form the highly reactive RNS peroxynitrite (ONOO −) that, unlike NO or O 2 •−, is a very …

Peroxynitrite is defined as a strong DNA oxidizing and nitrating agent, formed from the reaction of superoxide and nitric oxide, which can cause various types of DNA damage including strand breaks …

Peroxynitrite, the reaction product between nitric oxide (• NO) and superoxide, has been presumed to be a mediator of cellular and tissue injury in various pathological situations. It is formed at the …

The biochemistry of peroxynitrite is multifaceted, involving one- or two-electron oxidations and nitration reactions. This minireview highlights recent findings of peroxynitrite acting as a metabolic mediator in …